Search

Institutional Biosafety Committee

Getting Started

What are my responsibilities?

The IBC and the principal investigator each have specific responsibilities in assuring that biosafety concerns are identified and appropriately addressed throughout the research process.

What are my responsibilities as principal investigator?

  • The PI should make the initial determination of the required levels of physical and biological containment in accordance with the NIH Guidelines and the most recent edition of the BMBL (Biosafety in Microbiological and Biomedical Laboratories).
  • The PI should select the appropriate microbiological practices and laboratory techniques to be used for the research.
  • The PI should ensure that all staff listed have access to the currently approved protocol and have read the protocol before beginning work.
  • The PI should ensure that the staff listed on the protocol have sufficient knowledge and are sufficiently trained to safely perform the responsibilities for which they have been assigned.
  • The PI should ensure that the protocol participants fully understand the steps necessary following any spills or potential exposures with the agents described in the protocol.
  • The PI should immediately report any suspected BSL-3 or confirmed BSL-2 research-related illnesses as well as reporting any accidents, significant problems with or violation of the NIH Guidelines, for any biosafety level, to the Biosafety Office immediately.
  • Report to the Biosafety Office spills or accidents that fall under the “IBC Policy and Procedures on Reporting Laboratory Incidents”.

IBC Responsibilities

  • Reviewing research and teaching involving biohazards or recombinant DNA or synthetic nucleic acid molecules for compliance with the NIH Guidelines, recommendations in the BMBL and the policies of the IBC;
  • Notifying the Principal Investigator of the results of the IBC’s review and approval;
  • Lowering containment levels for certain experiments as specified in Section III-D-2-a Experiments in which DNA from Risk Group 2, Risk Group 3, or Restricted Agents are Cloned into Nonpathogenic Prokaryotic or Lower Eukaryotic Host-Vector Systems;
  • Setting containment levels as specified in Sections III-D-4-b, Experiments Involving Whole Animals, and III-D-5, Experiments Involving Whole Plants;
  • Periodically reviewing recombinant DNA or synthetic nucleic acid molecule research conducted at the institution to ensure compliance with the NIH Guidelines
  • Reporting any significant problems with or violation of the NIH Guidelines and any significant research-related accidents or illnesses to the appropriate institutional official and NIH’s Office of Biotechnology Activities (OBA) within 30 days, unless the IBC determines that a report has already been filed by the PI;
  • Immediately reporting any suspected BSL-3 or confirmed BSL-2 research-related illnesses, and any accidents or, significant problems with or violations of the NIH Guidelines to the appropriate institutional officials and NIH’s Office of Biotechnology Activities;
  • Reviewing any reports of spills or accidents that fall under the “IBC Policy and Procedures on Reporting Laboratory Accidents”, and
  • The IBC may not authorize initiation of experiments, which are not explicitly covered by the NIH Guidelines until NIH establishes the containment requirement.
RASD | Browser Recommendations | Webmaster | IU Emergency System | Office Information | Site Map